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Regeneron and Bayer Record Positive Top-Line Outcomes of Two Phase 3 Research with VEGF Trap-Eye Bayer Health care and Regeneron Pharmaceuticals, Inc. announced that in two parallel Stage 3 studies in individuals with the neovascular type of age-related macular degeneration , all regimens of VEGF Trap-Eye , including VEGF Trap-Eyes dosed every 8 weeks, successfully met the principal endpoint. The principal endpoint was statistical non-inferiority in the proportion of sufferers who managed eyesight over 52 weeks in comparison to ranibizumab. Further outcomes will be offered at the Angiogenesis Meeting in February 2011. Bayer Regeneron and Health care are preparing to submit regulatory applications for advertising approval in European countries and the U.S.